To start, you'll want to preheat your oven to 325°F - that's right, nice and toasty. Now, for a 12 lb turkey, you're looking at about 3-3 1/2 hours of cooking time, give or take. But, if you're stuffing that bird, you'll need to add some extra time to the mix.
And speaking of stuffing, let's get into the nitty-gritty. You see, when you stuff a turkey, the filling can actually affect the cooking time - who knew? It's all about the density of the stuffing, and how it conducts heat.
Fun fact: did you know that the first stuffed turkey is credited to the ancient Romans? Yep, they loved their meat, and they loved their stuffing even more - talk about a match made in heaven!